Reject urge, mean ultimately (5)
I believe the answer is:
spurn
'reject' is the definition.
(synonyms)
'urge mean ultimately' is the wordplay.
'urge' becomes 'spur' (I've seen this before).
'ultimately' indicates one should take the final letters.
The last letter of 'mean' is 'n'.
'spur'+'n'='SPURN'
(Other definitions for spurn that I've seen before include "Contemptuously reject" , "Reject scornfully, say unwanted suitor" , "Slight" , "Reject disdainfully" , "Repulse" .)