Sent up a Roman Catholic to state capital (5)
I believe the answer is:
accra
'capital' is the definition.
(capital of Ghana)
'sent up a roman catholic to state' is the wordplay.
'sent up' says the letters should be written backwards.
'roman catholic' becomes 'rc' (abbreviation for Roman Catholic).
'to state' becomes 'ca'.
'a'+'rc'+'ca'='arcca'
'arcca' reversed gives 'ACCRA'.
(Other definitions for accra that I've seen before include "Largest city of Ghana" , "Ghana's capital" , "West Africa capital" , "Ghanaian city" , "Main city of Ghana" .)